I am seriously impressed by Microsoft OneNote and the HP Tablet that I am now using. I realised I was creating quite a bit of waste paper from my notes – so have moved them electronically.
I have a workbook for work and one for personal tasks and sync the workbooks between my home and work folders which is really neat. I have been using this setup for several months (mostly using the keyboard although sometimes in meetings the stylus is a faster and easier way of capturing thoughts and diagrams).
Visio 2010 is pretty cool tool, I would have to say that Windows 7, Visio and OneNote are my top 3 Microsoft products right now!
Visio 2010 even has support for Inking and Multi-touch – http://blogs.msdn.com/b/visio/archive/2009/12/18/visio-2010-better-with-windows-7.aspx and the MS blog  has some other pretty handy tips: http://blogs.msdn.com/b/visio/